ravsta Posted March 11 Share Posted March 11 We need to make the extract with sativa not indica A cannabis extract has shown positive results in slowing down melanoma cell growth and increasing cell death rates, a new in-vitro study finds. Researchers from Charles Darwin University (CDU) and RMIT investigated programmed cell death caused by a specific cannabis extract (cannabinoid PHEC-66) from the cannabis sativa plant. The study that was part of a PhD project by RMIT’s Dr Ava Bachari found that the extract binds to receptor sites on particular melanoma cells, then controls the growth of cells at two pivotal phases and increases the amount of damage to the cells. CDU pharmaceutical lecturer and co-author Dr Nazim Nassar said this damage effectively manipulates the cell into killing itself. “The damage to the melanoma cell prevents it from dividing into new cells, and instead begins a programmed cell death, also known as apoptosis,” Dr Nassar said. “This is a growing area of important research because we need to understand cannabis extracts as much as possible, especially their potential to function as anticancer agents. “If we know how they react to cancer cells, particularly in the cause of cell death, we can refine treatment techniques to be more specific, responsive and effective”. Dr Nassar said the next challenge was developing targeted delivery system development to the melanoma cells to get it ready for pre-clinical trials. “Advanced delivery systems still need to be fully developed, underscoring the importance of ongoing efforts to ensure the proper and effective use of these agents at target sites,” he said. Dr Nassar specialises in cancer cell biology, pharmacology, drug delivery systems, and drug disposition and dynamics. A practising pharmacist and pharmacologist, he has co-authored several papers on applying cannabinoids in melanoma treatment, the therapeutic potential of cannabinoids in prostate cancer and an overview of current melanoma treatment. He said that while the use of cannabis extracts to treat a variety of health conditions is stigmatised, future research into its application could revolutionise cancer treatment. “Clinical uses of cannabis extracts include treatment for anxiety, cancer-related symptoms, epilepsy, and chronic pain. Intensive research into its potential for killing melanoma cells is only the start as we investigate how this knowledge can be applied to treating different types of cancers.” Lead author and RMIT biotechnologist Professor Nitin Mantri emphasised the necessity for a long-term follow-up to ensure the sustained effectiveness and safety of the PHEC-66 extract in cancer treatment over extended periods. He stressed the importance of testing the safety profile of the extract before its widespread adoption. "The subsequent stage involves animal studies or pre-clinical trials to validate and further explore the efficacy of cannabinoid PHEC-66 in treating melanoma and other cancers,” Professor Mantri said. He highlighted the critical collaboration with Dr Nassar, emphasising the need for support and sponsorship from pharmaceutical companies to qualify PHEC-66 as a registered medicine. This support is essential for advancing the development and application of cannabis extracts in cancer treatment, leveraging Dr Nassar's expertise as a healthcare professional, pharmacologist, and pharmaceutical scientist. https://www.cdu.edu.au/news/new-study-reveals-kill-order-melanoma-cells-cannabis-extract Phec-66 contains mainly CBD 9 Link to comment Share on other sites More sharing options...
monkeypig Posted March 11 Share Posted March 11 Did you men narrow leaf drug varieties? 1 Link to comment Share on other sites More sharing options...
Slippy One Posted March 11 Share Posted March 11 That stuff is harmful and will rot your brain 2 Link to comment Share on other sites More sharing options...
Mace_Windu Posted March 12 Share Posted March 12 Big Pharma has known about Cannabis's real therapeutic benefits/properties for many decades. Pharma drugs are about Patents, Money and Control not Medicine. 5 Link to comment Share on other sites More sharing options...
Cursed Posted March 12 Share Posted March 12 We definitely need a not for profit/public funded model or pharmaceutical R&D. 6 Link to comment Share on other sites More sharing options...
Boojum Posted March 12 Share Posted March 12 21 minutes ago, Cursed said: We definitely need a not for profit/public funded model or pharmaceutical R&D. Absoluteely. The for profit 'healthcare' model stifles and even prevents genuine research. Advocates of it would claim that it encourages 'competition' and so 'drives innovation' or some such arse gravy, but in reality a profit-based 'healthcare' system isn't interested in finding a cure for anything, if you cure something then you can only charge people once. What a profit-based 'healthcare' system wants is to manage the symptoms so the customer keeps coming back for more 'medicine', not cure the underlying problem (a conspiracy theorist might wonder what the pharmaceutical companies already have the cure for but are witholding because it makes them more money not to cure it and just keep treating the symptoms). Not to mention that the proprietary nature of research in a profit-based system slows development because scientists don't share ideas and data, and that the direction of research is not dictated by which illnesses are the most serious, or affect the most people, but which affect the richest who can pay the most money. 10 1 Link to comment Share on other sites More sharing options...
Shogun Posted March 12 Share Posted March 12 3 hours ago, Boojum said: What a profit-based 'healthcare' system wants is to manage the symptoms so the customer keeps coming back for more 'medicine', not cure the underlying problem (a conspiracy theorist might wonder what the pharmaceutical companies already have the cure for but are witholding because it makes them more money not to cure it and just keep treating the symptoms). That's all yesterday's news. It's all about prevention now. The vaccination business model proved to be very profitable. 1 Link to comment Share on other sites More sharing options...
Crow River Posted March 14 Share Posted March 14 If it's CBD, then as that's legal you can buy as much as you want. Or smoke/vape a 1:1 strain if you still want to get stoned. Or buy some "carp bait" and grow your own CBD rich hemp plants... 2 Link to comment Share on other sites More sharing options...
Mace_Windu Posted March 14 Share Posted March 14 10 hours ago, Crow River said: If it's CBD, then as that's legal you can buy as much as you want. Or smoke/vape a 1:1 strain if you still want to get stoned. Or buy some "carp bait" and grow your own CBD rich hemp plants... I'd go for the "Carp Bait" option for myself brother. You'll get much better nutrition and medical results from them than what's readily available in bottles on the high street. 1 Link to comment Share on other sites More sharing options...
Crow River Posted March 14 Share Posted March 14 6 hours ago, Mace_Windu said: I'd go for the "Carp Bait" option for myself brother. You'll get much better nutrition and medical results from them than what's readily available in bottles on the high street. Absolutely. You can eat the seeds themselves if you can't be bothered growing plants. Though maybe hemp seeds that are for human consumption would be better... I've done some test grows using seeds sold as bait, plants turned out just fine. They were all what we'd call regs so you can pollinate the girls and make your own seeds too. One thing I've noticed from reading into the hemp industry is that once you start making your own seeds, they're no longer licensed and are classes as cannabis rather than hemp. Presumably environmental factors during a grow might lead to plants producing more THC than the permitted minimum, for example. And that characteristic may be passed on to the next generation, etc. Hemp seed is as cheap as chips, so a good option for honing growing skills without costly mistakes... 4 Link to comment Share on other sites More sharing options...
Mace_Windu Posted March 14 Share Posted March 14 14 minutes ago, Crow River said: One thing I've noticed from reading into the hemp industry is that once you start making your own seeds, they're no longer licensed and are classes as cannabis rather than hemp. This is all to do with control as I mentioned in my very first post in relation to this subject. We the citizens must always have to rely on the industry/government for direction. We're deemed as unable to govern ourselves and to know what's best for our health, whilst they fleece us at every opportunity. 4 Link to comment Share on other sites More sharing options...
silvester growdrobe Posted March 28 Share Posted March 28 On 11/03/2024 at 13:01, ravsta said: We need to make the extract with sativa not indica A cannabis extract has shown positive results in slowing down melanoma cell growth and increasing cell death rates, a new in-vitro study finds. Researchers from Charles Darwin University (CDU) and RMIT investigated programmed cell death caused by a specific cannabis extract (cannabinoid PHEC-66) from the cannabis sativa plant. In this context all cannabis is cannabis sativa. 1 Link to comment Share on other sites More sharing options...
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