Hello wintermute,
I've done a 400W scrog and it worked fine, if I did it again I would make sure that I could get access to every side of the scrog using a modular system or movable walls etc. I did the 400 W scrog in a 3' x 3' footprint cupboard, with a gale blowing, using four plants in five gallon square containers; the plants at the back got less care and a bad attack of white fly. I would also advise using the same strain/variety first time for your sanity, I used affi, blueberry, C99 and aussie bush, so 100 % indica through to almost pure sativa, and it was a bit of a mess.
As an aside I've grown 16 plants in a 2' x 2' footprint, in 1 gallon square containers SOG, using a 250 w HPS and stadiuming and it worked quite well. But four seems more reasonable

U