Those hit found they could not get online after installing a Microsoft patch to close a security loophole.
Left open the flaw would have allowed malicious hackers to redirect users to fake websites, even if they typed the correct address.
Many net hardware and software firms prepared and applied patches this week to close the serious hole.
Firewall fix
The flaw in the net's Domain Name System (DNS) was discovered in March 2008 and since then many firms have been preparing patches and updates to ensure it cannot be exploited by hi-tech criminals.
On Tuesday Microsoft released its patch for DNS as part of its regular security update cycle.
However, many found that as soon as they applied the patch, known as KB951748, they could no longer go online.
BBC News website reader Chris Rogers applied the Microsoft patch to his own and his wife's computer but discovered that afterwards neither machine could get at e-mail or the web. His anti-virus software could no longer update either.
"Basically, the [Microsoft] update had crippled both PCs," he told BBC News.
The problems only affected those with machines running Windows XP or 2000.
A spokesman for Microsoft said PC owners were not contacting it about any problems the update caused.
Mr Rogers found restoring the PC's operating systems back to before the security update was installed, restored access to the net.
He, and many others, traced the problem to a conflict with the ZoneAlarm firewall.
As news of the problems spread, CheckPoint software, which owns ZoneAlarm, issued a statement about the problems.
While it prepared a fix for the fix, Checkpoint advised users to uninstall the Microsoft security update or temporarily lower the firewall settings to "medium".
Late on 9 July CheckPoint released an update to ZoneAlarm, version 7.0.483, that solved the conflict.
Mr Rogers said installing it and re-booting his machines fixed all the problems.
He said he could understand Microsoft being reticent with details about the patch given its sensitivity.
"But," he added "it would seem reasonable for [Microsoft] to test their patch against what is probably the most popular software firewall."
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