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soto
Hi,

It recently came to my attention that industrial hemp is known to have a high concentration of cannabidiol (CBD). Cannabidiol is an efffective non-addictive anxiolytic (anti-anxiety) and anti-psychotic drug and has been shown to be as effective as atypical anti-psychotics in treating schizophrenia.

I currently take an atypical anti-psychotic drug called 'quetiapine', however I am unhappy with both its side effects, the way it makes me feel and the possible long term complications of its use such as metabolic disorders. Thus, I'm drawn to using cannabidiol as a replacement, particularly because I have an anxiety disorder.

I could grow a nice indica with a little THC but that would be illegal, however hemp with a THC content 0.3% and below is legal in the UK to grow under licence.

Do you know of any industrial hemp seeds that have a very high CBD content or hemp oil that contains a high level of CBD?

If I were to grow I could look into seperating out the CBD using chromatography although I'd like to avoid this and growing altogether.
soto
http://www.kinesis.co.uk/bitem2.asp?catego...el2=Cannabidiol

http://www.caymanchem.com/app/template/Pro...talog/90080/a/z

unsure.gif

The cannabidiol brazilian paper in my first post says I need to take 1500mg daily if I have schizophrenia althougH I imagine the dose is lower for generalised anxiety.

Looks abit pricey though.
soto
I live in a shared house. I wonder if I could rent out an allotment lol.gif and plant a load of high strength CBD hemp.
Sam Semillia
QUOTE(soto @ May 14 2008, 03:49 PM) *
I could grow a nice indica with a little THC but that would be illegal, however hemp with a THC content 0.3% and below is legal in the UK to grow under licence.


You'll have to move heaven and earth before you get a licence bro. Stop fannying about and just grow some good ol fashioned herb. yahoo.gif

soto
Surely all I have to do is set up a business to sell hemp products?
podgy
QUOTE(soto @ May 14 2008, 02:53 PM) *
Surely all I have to do is set up a business to sell hemp products?


Unfortunately I suspect they'd make you jump through more hoops than you would want to... Pretty sure there's a thread round here somewhere where someone actually found a reference to getting a license to grow industrial hemp in the UK... They would more than likely restrict your ability to refine what your allowed to grow legally under this license, meaning they won't let you compete with the pharma companies or oil industry, but you can make all the rope you want... hitler.gif


Funny they upped its class over there to save people from going nuts and you've got all of this stuff that claims the plant has attributes to help alleviate (sp?) the conditions of the very disorder they claim it induces!!!! I just don't see how this plant can do both and suspect the other side of the fence is full of shit as usual..
soto
ah yes of course. Theoretically if you could extract enough CBD from industrial hemp, you could do what they're doing with sativex but for mental health, however that would cost a fortune.

It may be worth getting on the backs of GW (guys who produce sativex) to provide a pure CBD extract for those with mental health problems. The paper I quoted shows that it may not be difficult to prove the efficacy of such a medicine and I think GW would be very interested in this, they would make abit of money off the back of it.
podgy
It's probably nothing they weren't aware of well before it hit the eyes of the public... This plant we love has so many potentially positive contributions to society yet it threatens the exhistence of every corperate entity that it's benefits compete with so here we sit with a demonized panacea that half the world believes will make us mad, or is making us mad (always seems to pacify me)...

Their alternative synthetic pills make more money for them and provides plenty of tax write-offs in R&D,trials, & testing with what I'm sure will be less than spectacular results, but they make 100% profit off every pill they sell cause they're writing off ALL (yeah they write it all off on the corperate level) their production costs... Which in turn makes for a golden Profit & Loss statement that shareholders will swoon over and trade more of their stock because of...
If a comparison trail were done including the sacred plant on a level playing field (I have yet to see a so-called comparison study that effectively studies both canna and whatever they are comparing it to that didn't have enough baises or oversights resulting in a major disadvantage to the canna-side of the experiment/study) I belive weed would blow the doors off of any of its competitors. I wouldn't be doing what I do if I didn't... There is still the whole cost effectivness in some of its legitimate uses (anything, but just to get silly would be legitimate in my book, err not that there's anything wrong with that either) like an alternate fuel source might be over the top at this point in time as there are probably more vehicles out there than we could grow weed for to move around at the rate most of us like to go or need/have to go..

But it is here in the medicnal arena that I'm truely mythed by the method to the governments madness over weed... They know what its potential benefits are,but they are reluctant to employ a policy of free trade as it will damage the very people's businesses that helped them to get into office..
oldskoolloner
QUOTE(soto @ May 14 2008, 03:49 PM) *
Hi,

It recently came to my attention that industrial hemp is known to have a high concentration of cannabidiol (CBD). Cannabidiol is an efffective non-addictive anxiolytic (anti-anxiety) and anti-psychotic drug and has been shown to be as effective as atypical anti-psychotics in treating schizophrenia.

I currently take an atypical anti-psychotic drug called 'quetiapine', however I am unhappy with both its side effects, the way it makes me feel and the possible long term complications of its use such as metabolic disorders. Thus, I'm drawn to using cannabidiol as a replacement, particularly because I have an anxiety disorder.

I could grow a nice indica with a little THC but that would be illegal, however hemp with a THC content 0.3% and below is legal in the UK to grow under licence.

Do you know of any industrial hemp seeds that have a very high CBD content or hemp oil that contains a high level of CBD?

If I were to grow I could look into seperating out the CBD using chromatography although I'd like to avoid this and growing altogether.


I like you would like to change my meds I am on the same as you quetiapine. though growing industrial hemp you will need a form of extraction to create a monotherapy as there are around 40 cannabidiols in hemp.

where did you get 1500mg cbd i wonder how much plant matter that would be?

the french study that I havent found yet were supposedly were on a low dose.

Like of current study
http://www.420magazine.com/forums/medical-...hotic-drug.html
Karmacollector
QUOTE(oldskoolloner @ Sep 5 2008, 06:38 PM) *
QUOTE(soto @ May 14 2008, 03:49 PM) *
Hi,

It recently came to my attention that industrial hemp is known to have a high concentration of cannabidiol (CBD). Cannabidiol is an efffective non-addictive anxiolytic (anti-anxiety) and anti-psychotic drug and has been shown to be as effective as atypical anti-psychotics in treating schizophrenia.

I currently take an atypical anti-psychotic drug called 'quetiapine', however I am unhappy with both its side effects, the way it makes me feel and the possible long term complications of its use such as metabolic disorders. Thus, I'm drawn to using cannabidiol as a replacement, particularly because I have an anxiety disorder.

I could grow a nice indica with a little THC but that would be illegal, however hemp with a THC content 0.3% and below is legal in the UK to grow under licence.

Do you know of any industrial hemp seeds that have a very high CBD content or hemp oil that contains a high level of CBD?

If I were to grow I could look into seperating out the CBD using chromatography although I'd like to avoid this and growing altogether.


I like you would like to change my meds I am on the same as you quetiapine. though growing industrial hemp you will need a form of extraction to create a monotherapy as there are around 40 cannabidiols in hemp.

where did you get 1500mg cbd i wonder how much plant matter that would be?

the french study that I havent found yet were supposedly were on a low dose.

Like of current study
http://www.420magazine.com/forums/medical-...hotic-drug.html

Guys reading this is interesting. For many many years i have considered myself bipolar but have never sought diagnosis because cannabis allieviates the symptoms, but after reading your comments i am wondering if i may not be bi polar.... I prefer the effects of higher concentrations of CBD in my smoke to the Paranoia inducing THC. I fair better on sativas than indicas. Any chance of any tips....or an online diagnosis!! lol.gif biggrin.gif
tony2wheelsgood
QUOTE
Do you know of any industrial hemp seeds that have a very high CBD content or hemp oil that contains a high level of CBD?


why not contact the bloke down in devon who grows the crops for "good oil". he's happy to hear from punters and he's very pro canna/hemp. if anyone in uk can guide you it'll be him imo. you could also shortcut the process of getting a licence by buying the relevant seeds direct from the breeder so no illegality involved and your head is still below the parapet.
oldskoolloner
QUOTE(tony2wheelsgood @ Sep 5 2008, 07:10 PM) *
QUOTE
Do you know of any industrial hemp seeds that have a very high CBD content or hemp oil that contains a high level of CBD?


why not contact the bloke down in devon who grows the crops for "good oil". he's happy to hear from punters and he's very pro canna/hemp. if anyone in uk can guide you it'll be him imo. you could also shortcut the process of getting a licence by buying the relevant seeds direct from the breeder so no illegality involved and your head is still below the parapet.



Here are the two varietys of cannabis with very high CBD and very very very low THC, not enough to even get you high cannibis
These strain are what you get in bird seed and in food shop. They are class as industrial hemp

Cannabis. sativa subsp. sativa var. sativa
Cannabis. sativa subsp. sativa var. spontanea
oldskoolloner
QUOTE(tony2wheelsgood @ Sep 5 2008, 07:10 PM) *
QUOTE
Do you know of any industrial hemp seeds that have a very high CBD content or hemp oil that contains a high level of CBD?


why not contact the bloke down in devon who grows the crops for "good oil". he's happy to hear from punters and he's very pro canna/hemp. if anyone in uk can guide you it'll be him imo. you could also shortcut the process of getting a licence by buying the relevant seeds direct from the breeder so no illegality involved and your head is still below the parapet.

who is this bloke down in devon
oldskoolloner
QUOTE(oldskoolloner @ Sep 5 2008, 10:31 PM) *
QUOTE(tony2wheelsgood @ Sep 5 2008, 07:10 PM) *
QUOTE
Do you know of any industrial hemp seeds that have a very high CBD content or hemp oil that contains a high level of CBD?


why not contact the bloke down in devon who grows the crops for "good oil". he's happy to hear from punters and he's very pro canna/hemp. if anyone in uk can guide you it'll be him imo. you could also shortcut the process of getting a licence by buying the relevant seeds direct from the breeder so no illegality involved and your head is still below the parapet.



Here are the two varietys of cannabis with very high CBD and very very very low THC, not enough to even get you high cannibis
These strain are what you get in bird seed and in food shop. They are class as industrial hemp

Cannabis. sativa subsp. sativa var. sativa
Cannabis. sativa subsp. sativa var. spontanea

here is another variety I have found out about
Cannabis oglalas


tony2wheelsgood
QUOTE
who is this bloke down in devon
if you go in sainsburies (and others) you'll see "Good Oil" which is cold pressed hemp oil. it's grown in north devon by a bloke whose name i can't remember but who was very helpful when i emailed him about using hemp oil on skin conditions in cats (i know, sounds weird).
google good oil and all will be revealed.
oldskoolloner
QUOTE(tony2wheelsgood @ Sep 6 2008, 06:48 PM) *
QUOTE
who is this bloke down in devon
if you go in sainsburies (and others) you'll see "Good Oil" which is cold pressed hemp oil. it's grown in north devon by a bloke whose name i can't remember but who was very helpful when i emailed him about using hemp oil on skin conditions in cats (i know, sounds weird).
google good oil and all will be revealed.


Thanks for your help!
soto
Thought I'd brielfy update this thread.

Please note these key findings of the initial study.

QUOTE
patients. In
1995, CBD was tested in a case study with a
19-year-old schizophrenic female patient
who presented serious side effects after treatment
with conventional antipsychotics (47).
Following a wash-out period of 4 days this
patient received increasing oral doses of CBD
dissolved in oil, reaching 1500 mg/day, for 4
weeks. After this period, CBD administration
was interrupted and placebo was administered
for 4 days. Finally, the treatment was
shifted to increasing doses of haloperidol
that reached 12.5 mg/day. The psychiatric
interviews were video-recorded and the
symptoms were assessed by a blinded-psychiatrist
using the Brief Psychiatric Rating
Scale (BPRS). A significant improvement
was observed during CBD treatment,


If you were to try and extract 1500mg of CBD from hemp oil I have discovered the cost would be astronomical. However do any of those of you who use cannabis that has a high CBD content know approximately how much CBD you are consuming? Because you're clearly experiencing the anti-psychotic anxiolytic effect of the CBD.

This table shows the typical chemical composition of hemp oil



As you can see, there is 10mg of CBD in each kg of hemp oil.

You can buy hemp oil for about £10 for five litres from fishing shops . However you can even import it by the gallon..... 10mg/kg is way too low though if you need 1500mg to treat schizophrenia, however the dose required may be lower for other conditions.

Even if you obtained this hemp oil cheaply and in bulk, you've still got to perform chromatography to extract the CBD. Which I imagine is a costly and difficult experience. I'm also not sure on the legality of extracting the CBD. I mean, it's a metabolite, thus you can turn it into THC using some chemicals....... Not that this is what I'm suggesting.

Thus, it's extremely infeasible to use CBD from hemp oil to treat medical conditions.

The only other option I can see is trying to get hold of actual industrial hemp. Which should have quantities of CBD similar to that in Marijuana. I can't see anywhere selling industrial hemp in its raw form on the net, and as for extracting the CBD from raw industrial hemp. lol.gif. I guess you could smoke or vapourize it....

I must say this raise the question of what the penality would be were an individual to grow industrial hemp? I guess you could just say you accidently threw some bird seed into the garden? If you were prosecuted you could also point them to that incident the press reported where a little girl had planted a cannabis seed from bird seed etc and the authorities chose not to prosecute the parents......
soto
Does anyone know of any records which show accounts of where people have been prosecuted for growing industrial hemp.

If I grew industrial hemp to extract cannabidiol and was prosecuted, I imagine one could still attempt a challenge of the charges on grounds of medicinal use of cannabidiol.

The medicinal properties of THC are much higher than CBD as THC can be used to treat a much wider range of conditions and it's troubling that medicinal use of THC has never really been accepted by the courts.

However I don't think anyone has ever tried to challenge the basis of prohibiting CBD for medicinal use. I would be interested to see this tested in court, however I don't think the evidence for CBD as an anxiolytic/anti-psychotic is strong enough to mount a defence.

It's absurd enough to get a criminal record for growing cannabis. Having a similar criminal record for growing hemp as a medicine would be even more absurd.
soto
Also surely the fact that I can BUY CBD in small amounts from fishing shops in the form of hemp oil would make the whole criminal proceedings look abit farsicle. I guess the same could be said for the THC but that really is in TINY amounts in industrial hemp.

I gather THC4MS et al. have well established that the courts in the UK do not consider medicinal use of cannabis as a proper defence. Does the whole cannabis genus come under those ruling?
Chris P
Interesting post. It doesn't look like hemp oil is a useful source of CBD. Hemp oil is made from the seeds.

Extracting CBD using gas chromatography would be very time consuming. There is a video on youtube of some cannabis gas chromatography results, you can buy a kit to do it. To do it at a higher purity would be very expensive. Like you say though, it would be better to get the chemical into your system another way, like ingestion or smoking.
They show CBD levels of some strains on the Greenhouse website, it was very low in the strains I looked at. Some strains do contain some though.

If you want to grow and experiment you might as well do it with a mix of THC strains, so you can see which plant medicine combination suits you best. It's the terpenoids and flavenoids and other aromatic molecules which also contribute to the effect. If you want to be medicated with cannabinoids you can be a connoiseur. Growing yourself you can harvest at different times if you want as the cannabinoids change throughout the growing cycle, to find a medicine that suits you best.

If you want to smoke hemp that's up to you, it may have some antipsychotic effect, although I'm thinking next of growing Lemon Skunk, Cheese, Great White Shark, etc, etc. Whether they contain any CBD or not I don't really care, I'll decide if I like the strain or not when I smoke it.
soto
Aye. Also the approximate cultivated CBD values on websites probably leave a lot to be desired and as you say there are all sorts of factors to take into account. I'm drawn to suomi hemp.

This cracks me up.

QUOTE
Farmers low at hemp ban for cows

By Alan Little
BBC News, Liechtenstein

Cows eating hemp
Calm cows have higher milk yields, say hemp farmers
Liechtenstein milk farmers have been stirred up by a government ban on their feeding hemp to their cattle.

They are the most chilled-out, laid-back, carefree cattle in the world, and happy cows produce better milk.

What is it that keeps the cash cows calm? Hemp, which is related to cannabis. And that's why Liechtenstein has banned its use.

This has in turn enraged the country's dairy farmers, who say that the hemp relaxes those jangly bovine nerves.

Hemp farmers are less then mellow about the new law.

"Hemp is good for cows because it is serves as a very small tranquiliser," says hemp farmer Jean-Pierre Egger.

"Many of the cows are stressed nowadays. If they eat hemp, they calm down. Now, a milk cow which is calm produces better milk. That is a fact."

No high

In neighbouring Switzerland, hemp is grown legally for industrial purposes but farmers are also banned from feeding it to cattle.

The authorities there say the trouble is that a chemical called THC - the chemical that helps give the "high" associated with cannabis use - can get into the milk.


The only thing which gets high is the quality of milk and the quality and general health of the cow
Jean-Pierre Egger
Hemp farmer

Peter Malin, of the Liechtenstein Department of Agriculture, has similar concerns.

"We don't want to have to contaminants such as THC which doesn't occur naturally in milk," he said. "And we don't want it to be consumed by people, especially by children."

But farmers say this European hemp has none of the narcotic properties found in its Indian cousin.

The cattle here may be relaxed, but they are not stoned.

"The only thing which gets high is the quality of milk and the quality and general health of the cow. That's how high the cows are feeling," says Mr Egger.

But there are some other dairy-cow farmers who are sceptical about the milk-yield benefits of hemp. They welcome the ban.

Dairy farmer Simon Schiprscher says he never feeds his cows hemp.

"I thought the people that did were a bit exotic and alternative," he said.

So consumers of Swiss chocolate and Gruyere cheese can, well, relax.

For the cows who will have to change their diet though, life is about to become a little less laid back.




source

QUOTE
Peter Malin, of the Liechtenstein Department of Agriculture, has similar concerns.

"We don't want to have to contaminants such as THC which doesn't occur naturally in milk," he said. "And we don't want it to be consumed by people, especially by children."


rofl.gif rofl.gif

Children getting high drinking milk from cows who ate industrial hemp.....

Honestly, the thoughts that must be going through that man's mind.



Really would be bloody reefer madness.
Grimweeder
why not try crossin a hemp variety with high cbd with a skunk strain with low cbd, you should get offspring that give a mix of higher cbd/thc an vice versa
as far as im aware the highest cbd content of any strain that has thc an gets you high is only about 1.5% anyways an the average is around 1% usually less.



ununnilum
According to the wikipedia article, cannabidiol is soluble in organic solvents so you could just make "butane honey oil" from hemp and it will be extracted along with any other cannabinoids present in the hemp.

QUOTE (soto @ May 14 2008, 06:31 PM) *
I live in a shared house. I wonder if I could rent out an allotment lol.gif and plant a load of high strength CBD hemp.


One of my grandma's favourite stories was how her father grew cannabis on his allotment is the late 1960's. When the police came knocking, he told them a "man down the pub" had been growing it and had recommended it for drainage. Rather surprisingly they let him go. rofl.gif He later took to growing it in his garden.
oldskoolloner
QUOTE (tony2wheelsgood @ Sep 6 2008, 06:48 PM) *
QUOTE
who is this bloke down in devon
if you go in sainsburies (and others) you'll see "Good Oil" which is cold pressed hemp oil. it's grown in north devon by a bloke whose name i can't remember but who was very helpful when i emailed him about using hemp oil on skin conditions in cats (i know, sounds weird).
google good oil and all will be revealed.

I am afraid I tried no response, and that was a long while ago :-(
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