[Irrelevant]

I got this information from a reliable source.
cant give names or email adresses, but let's just say it is this mans job to know these things..

 Tomas, on 15 April 2012 - 04:33 PM, said:

 Psycho-tik, on 15 April 2012 - 12:40 PM, said:

{....
CBD can't be absorbed by ingestion. Vapourizing or smoking are the only routes for CBD. }

That specific period of time in wich i stopped using citalopram I smoked a rough 3 grams of high CBD weed a day.

Hello Psycho-tik,

do you have some information - why ingestion is no way to absorb CBD? I'm very interested in CBD, I tried some industrial hemp oil (ingestion) and
the effect was much worse I could imagine before.

Do you have some scientific information - links or something like that?

Its the first time I read that CBD is not absorbed by ingestion...

All the best

[vape_ninja]

I PM'ed you, and basically my idea is to have a high L-Tryptophan diet, L-Tryptophan --> 5-HTP --> Serotonin.
That would help raise serotonin levels, although depression can also be dopamine related too.

I live on a high Tryptophan diet, and i have found it does help you in quite a few ways really. More energy, more concentration and immune system is very good

This post has been edited by vape_ninja: 15 April 2012 - 08:50 PM

[Sawney Bean]

 Psycho-tik, on 15 April 2012 - 12:40 PM, said:

HI there,
I have also had citalopram as a medication .
Strains high in CBD allowed me to stave off the citalopram.
Eventually my medication became cannabis again for a while.
Looking back it seems as if smoking strains high in CBD in combination with slowly (!) weening of the cita's causes a slow but long term change in my case.

I scraped of a tiny bit each time i had to ingest the pill.
eventually i was ingesting a crumbsized bit and quit.
The 3 days after the last pill i felt a bit edgy and slept/stayed in bed till it was over.

{ sometimes i read on this board that strains hiigh in CBD are mostly indica. This is not the case. It seems as if the highest cbd levels are found in sativas and it's hybrid offsprings. Even higher levels of CBD can be found in strains crossed with OTTO. Using a male hemp plant while crossing with any high THC strain female will eventually yield strains with exceptionally high CBD levels.
CBD can't be absorbed by ingestion. Vapourizing or smoking are the only routes for CBD. }

That specific period of time in wich i stopped using citalopram I smoked a rough 3 grams of high CBD weed a day.

 Psycho-tik, on 15 April 2012 - 06:57 PM, said:

I got this information from a reliable source.
cant give names or email adresses, but let's just say it is this mans job to know these things..

C'mon you must have more information than that bro? If CBD cant be absorbed by ingestion, then why is it a key ingredient in sativex?

[fredaweed]

SSRI'S are terrible, I had a horrible experience with citalopram, as have friends that have also been prescribed this shit.
It made me more depressed initially, Made me tremor like a human vibrator and also made me really anxious and paranoid, leading onto agoraphobia, among other things which miraculously stopped a few months after I stopped taking it.

I quizzed my GP about this, he said it was rare to react like this, which is bollocks. I looked on forums and found loads of people that had the same unwanted side effects as me, I also have friends that reacted badly to it.

Doctors don't know a lot about the drugs they push, some would rather send you on your way with a prescription than get to the root of your depression and do their fucking job, Without getting to the root, you'll still be depressed mate.

I just smoke more, a lot more and it works very well for me

[camerasforears]

IMO I think that you should try giving up the puff for a while to be honest. If your doctor thinks you warrant SSRI's then don't thrown down something continually on top of the effect it is having on your brain.

I have tried Citalopram and other SSRI's in the past and I can say they do work, you just have to give them time (2 months) and the effect is not that pronounced but more nuanced. Sometimes with smoking the jazz cigarettes all day you can get listless, they are not for everyone and it is good to to a break now and then no matter how much you like something. i.e. everything in moderation. Whether that be crack, computer games or fish and chips..

You might find you have more energy without the puff everyday and in fact just being active can help reduce any signs of depression. One thing I can say about SSRIs is they do work for nearly all people, you just need to find the right balance/chemicals for your own brain and not see it as some stigma about taking a daily medication. However it is just the same as anything else, if you will it not to work or think it won't then the placebo effect comes into play. If you can take a swedger and get a reaction then SSRIs will work on your brain. It's not the exact same chemically but both require serotonin release and absorption..

I imagine the doctor has recommended some lifestyle changes in combination so perhaps giving your lungs a rest would help to facilitate those other things as well. You can't just take a pill and feel better but hopefully it will help you on your way. I wish you the best for what is troubling you and a more happy future!

[Tomas]

 Psycho-tik, on 15 April 2012 - 06:57 PM, said:

I got this information from a reliable source.
cant give names or email adresses, but let's just say it is this mans job to know these things..

 Psycho-tik, on 15 April 2012 - 12:40 PM, said:

{....
CBD can't be absorbed by ingestion. Vapourizing or smoking are the only routes for CBD. }

That specific period of time in wich i stopped using citalopram I smoked a rough 3 grams of high CBD weed a day.

It could explain some things, but I wonder why so many epileptics benefit from ingested CBD medicine if it would not work?

On the other hand the studies about psychosis/schizophrenia and CBD - also ingested CBD - not smoked.

But to me- I tried several times - I had the feeling that smoked was better than ingested, but ingested did last longer.

I need it for my anxiety problems and (roughly) schizophrenia.

At the moment I'm on antidepressants/anxiolytic and antipsychotics...

All the best

[namkha]

 Psycho-tik, on 15 April 2012 - 12:40 PM, said:

CBD can't be absorbed by ingestion. Vapourizing or smoking are the only routes for CBD. }

sorry Psycho-tik, but it's not so surprising that you can't back that up with sources, as you've got your facts wrong

sure, no cannabinoids are absorbed efficiently by ingestion --- but, oral bioavailability for CBD is about 6%, which is the same as for THC

if eaten in fats and oils, absorption will be better

google "CBD bioavailability"

somewhere up the top of the Page rankings you should get p. 220 of 'Medicinal Uses of Cannabis and Cannabinoids'

smoking does give you better bioavailability for CBD - about 31%

but the most efficient routes of administration for all cannabinoids, including CBD, is sublingually and rectally --- closer to the 60% region

@Tomas --- the CBD in Sativex is absorbed sublingually - under the tongue

This post has been edited by namkha: 16 April 2012 - 02:01 AM

[vape_ninja]

How to raise Serotonin with Foods + Sunlight
(also raises Melatonin i believe)

Eat these foods here, as they are high in L-Tryptophan, But also make sure that you are eating Carbohydrates + Starch in your diet as well. Rice, Potatoes, Pasta. This will help the conversion process. What happens is, that all of the other Amino acids get pushed into the muscles, leaving L-Tryptophan first in line to get converted.

http://upload.wikime...iosynthesis.svg

Sunlight is also a key factor in the conversion process. If not i believe that it all gets converted to Melatonin.

Dark Chocolate (60% cocoa minimum) Do Not consume more than 25g a day.
Chicken
Turkey (*Myth*one of the best foods at raising serotonin, and my theory why people fall asleep after a chistmas dinner is that it raises your serotonin levels that high after eating so much turkey)
Milk (A nice warm cup/glass of milk near bedtime will help you sleep also)
Tuna
High omega 3 foods that increase serotonin like wild salmon, sardines or Mackerel
High Quality Eggs
Cheese
Bananas (Best to eat when fresh, higher starch content, less sugar)
Whey protein (Like that in protein shakes)
Sour Cherries - Raises Serotonin levels + Melotonin
Free Range Beef
Asparagus
Avocado
Pecans
Pineapple
Eggplant
Spinach
Walnuts
Roasted pumpkin seeds
dry sunflower seeds
Oats
Kidney beans


The Upside to this diet is that it won't have the nasty Side effects of anti-depressants.
I was on Citalopram myself. For 2 weeks only however as i was having severe side effects! Altered vision at sundown, Full on body disassociation (Riddled with Anxiety!!!)
You should give the diet at least 3 weeks till it starts taking action really, Creativity is key also!

One of my favourite things to make is a Banana, oat and milk smoothie. Delicious perfect for after a workout.

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This post has been edited by vape_ninja: 16 April 2012 - 09:21 AM

[WaxingGibbous]

Had a nasty event that left me with a disability a couple of years ago, the trauma put me on Citralopram for a year.

Wasn't well enough for smoking weed for about three months, (didn't want to chance any meltdowns) but I found a nice Volcano to be rather comforting when I finally indulged. However, the buzz is different in my experience, there is a definite Citralopram tang to the experience and I found I was smoking incessantly rather than having a hit and letting it roll. Unlike alcohol, the medical community generally don't think there is a significant interaction between Citralopram and THC.

Eventually I managed to wean myself off the tablets and found herbs a very useful tool in my kit for doing this. Citralopram was a useful medication for stopping the PTSD nature of my illness but I found it kind of froze me up emotionally, it's nice to be on the other side

[rune]

 Jamesbong, on 15 April 2012 - 04:02 PM, said:

On another note, they've made him stupidly tolerant to MDMA so keep away from that unless you want to waste some money.

SSRIs are known to stop MDMA from working. This is due to the fact that they are both involved with Serotonin ( i won't go into the minute details here ;-) ). Chasing a buzz with MDMA whilst on SSRIs could be dangerous as it could cause you to consume way over the safe amount of MDMA.

If you're on SSRIs, best to stay off of MDMA.

In fact, it's a good idea to give MDMA a break anyway if you're suffering from depression.


However, 5-HTP is a natural Serotonin precursor which can also can enhance, not destroy the MDMA buzz and also protect the brain from some of the harmful effects of MDMA. There's plenty of info online.

rune

[Niceguysi]

I have been using citalopram for 12 months now after being made redundant from a long term job. Im not suicidal,or heavily depressed i just couldnt cope with not knowing if i could get by in life as i dont have any family. The first citalopram tablet i took started working straight away,i didnt think about all the negative stuff like before. They have completely changed my life and my ability to cope with life's pressures. Im not a heavy smoker just the odd spliff,it hasnt affected me at all,i think it is all about finding balance between the two. Good luck for the future.If you risk nothing you will gain nothing.

[bill cooper]

i found citalopram helped me stop dwelling on thing's as much and definetly helped me mentally unfortunatly they also made me lose my sex drive, pile the weight on and sleep all day
so apart from turning into a fat impotent rip van winkle they did work but i changed to seritone or something like that which helped without the side affect's which iv since stopped as well good luck i hope you find one's that work for you

[Smurfy]

 bill cooper, on 16 April 2012 - 02:30 PM, said:

i found citalopram helped me stop dwelling on thing's as much and definetly helped me mentally unfortunatly they also made me lose my sex drive, pile the weight on and sleep all day
so apart from turning into a fat impotent rip van winkle they did work but i changed to seritone or something like that which helped without the side affect's which iv since stopped as well good luck i hope you find one's that work for you

yeah i hear ya about sex drive mate, well to be honest it didnt really completely disappear, but found it really difficult...to um how should i say this...shoot me bolt

[bill cooper]

ditto

[lovemaryj71]

Bugger me reading this thread has put me off anti depressants forever!

Its as though you just take a risk and maybe itll work maybe it wont!

The symptoms seem horrendous in some cases how can it be ok to play this sort of russian roulette with peeps lives!

I have a mate who has agrophobia and he just doesnt go out any more!

Its hard to watch how he suffers sometimes

My thoughts go out to all the peeps suffering with these mental issues.

Peaceout